Abstract
Objective: The study systematically evaluated the effects of Baduanjin with different time, frequency and cycle on glucose and lipid metabolism in patients with prediabetes of different ages. Methods: Randomized controlled trials (RCTs) on the effect of Baduanjin exercise on PDM patients were comprehensively searched in PubMed, Embase, CNKI and other databases. The retrieval time was from the establishment of the database to September 2022. Results: a total of 13 items of RCT were included in this study, including 415 patients in the trial group and 405 patients in the control group. The results of Meta-analysis showed that FPG (MD-0.45, 95%CI:-0.60, P<0.0l), P < 0.05.The results showed that Baduanjin was superior to the control group in fasting blood glucose in patients with prediabetes, and TG (MD=-0.29,95%CI:-0.52 Baduanjin was better than the control group in improving triglyceride (TG). HDL-C (MD=0.06,95%CI:0.02~0.11,P < 0.01), P < 0.05.Results showed that the intervention group of Baduanjin was superior to the control group in improving high density lipoprotein cholesterol (HDL-C) in patients with prediabetes. LDL-C (MD=-0.27,95% CI:-0.44~-0.10,P=0.002), P < 0.05.The results showed that the intervention group of Baduanjin was superior to the control group in improving low density lipoprotein cholesterol (LDL-C) in prediabetic patients. The results of TC (MD=--0.36,95%CI:-0.60~-0.12,P=0.004 < 0.05) showed that the intervention group was superior to the control group in improving serum total cholesterol (TC) in patients with prediabetes. The results of subgroup analysis showed that when the age of the patients<60 years old, the intervention time ≥ 60 minutes, the intervention period ≥ 6 months and the intervention frequency ≥ 5 days, the Baduanjin was superior to the control group in improving the indexes of prediabetes. Conclusion: Baduanjin can further improve the level of glucose and lipid metabolism in patients with prediabetes, especially in FPG, TC, HDL-C and LDL-C.
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