Evaluation of the effectiveness of non-drug methods of hypercholesterolemia treatment

Abstract

Hypercholesterolemia is one of the most common pathological conditions and plays a signifi cant role in the development of cardiovascular diseases, arterial hypertension (AH), type 2 diabetes mellitus, etc. The aim of the study was to evaluate the population potential of non-drug methods for cholesterol level correction. Material and methods. 3 groups were formed on a voluntary basis out of the 2013 initially surveyed people with high cholesterol (˃ 6.4 mmol/l). In the 1st group, consisting of 89 residents, it was recommended to reduce the energy value to less than 2500 kcal/day. The 2nd group consisted of 92 residents who agreed to a daily increase in physical activity (PhA) to reduce the high level of cholesterol (˃ 6.4 mmol/l). In the 3rd group, consisting of 96 residents, both measures were recommended, i. e. not to exceed the energy value of the food intake and increase daily physical activity. Control studies of cholesterol level were carried out 6–8 months after starting the work. Results and discussion. In the 1st group of residents the diff erence in cholesterol levels at the beginning of work and 6–8 months after its completion was 10.6 ± 1.3 and 6.6 ± 0.7 mmol/l, (t = 2.70; p ˂ 0.01) respectively. In the 2nd group of residents a decrease in the cholesterol level was noted as well — from 9.7 ± 0.9 to 6.6 ± 0.6 mmol/l (t = 2.87; p ˂ 0.01). Group 3showed a similar decrease in the level of cholesterol level from10.4 ± 1.1 to 6.9 ± 0.8 mmol/l (t = 2.59; p ˂ 0.01). Thus, non-drug therapy provides a noticeable decrease in cholesterol level, which is of great importance, they do not provide the achievement of the classical norm of cholesterol level (˂ 5.0 mmol/l). Conclusions. Non-drug correction of cholesterol is quite effective. It is necessary to fi nd accessible ways to increase preventive motivation, medical awareness of the population, adherence to therapeutic and preventive measures and assess the quality of life in accordance with the dynamics of changes in cholesterol levels.