Abstract
Objective: To evaluate left ventricular regional and global systolic function by measuring left ventricular longitudinal strain (LS) in hypertensive patients with sigmoid-shaped interventricular septum (SIS) by two-dimensional speckle tracking (2D-STE); in order to explore whether the sigmoid-shaped interventricular septum affects the left ventricular systolic function in patients with hypertension. Methods: Routine echocardiographic parameters were measured in 30 hypertensive patients with SIS (SIS group) and 30 hypertensive patients without SIS (non-SIS group). The left ventricular segments and global LS were measured by 2D-STE, and the two sets of parameters were compared. Results: The value of the thickness of the basal segment of the interventricular septum (IVSBT), the thickness of the middle segment of the interventricular septum (IVSMT) and the ratio of the basal segment of the ventricular septum to the middle segment of the interventricular septum (IVSBT/IVSMT) in SIS group was higher than that in non-SIS group. However, the value of left ventricular outflow tract diameter (LVOTD) in SIS group was lower than that in non-SIS group. There was a significant difference between the two groups (all P < 0 05). The LS values of the basal segment of the left ventricular anterior wall and the posterior wall of the left ventricle in the SIS group were lower than those in the non-SIS group. The difference was statistically significant (all P < 0.05). Conclusion: SIS affects left ventricular regional systolic function of patients with hypertension. 2D-STE can early evaluate left ventricular longitudinal systolic function in hypertensive patients with SIS.
Highlights
Sigmoid-shaped interventricular septum (SIS) was first proposed by Goor et al [1] in 1969
To evaluate left ventricular regional and global systolic function by measuring left ventricular longitudinal strain (LS) in hypertensive patients with sigmoid-shaped interventricular septum (SIS) by two-dimensional speckle tracking (2D-STE); in order to explore whether the sigmoid-shaped interventricular septum affects the left ventricular systolic function in patients with hypertension
The results showed that in the SIS group, except for the obvious thickening of the base of the interventricular septum, the thickness of the other ventricular wall was approximately normal, and the decrease of the inner diameter of the left ventricular outflow tract suggested that it might be re
Summary
Sigmoid-shaped interventricular septum (SIS) was first proposed by Goor et al [1] in 1969 It refers to the local thickening and protruding to the left ventricular outflow tract at the base of the interventricular septum, resulting in the shape of S-shaped blood flow through the left ventricular outflow tract. In the observational study of SIS, the prevalence rate of hypertension is often between 55% and 85% [2] [3] [4]. There is no consensus on the clinical significance of SIS [5]. It is not clear whether SIS affects left ventricular systolic function in patients with hypertension. The purpose of this study was to evaluate the left ventricular regional and global systolic function in hypertensive patients with SIS by 2D-STE, and to explore whether SIS affects the left ventricular systolic function in hypertensive patients
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