Abstract
This study simulated the process of in vitro digestion of ethanol extract from Gastrodia elata. After simulated oral digestion, gastrointestinal digestion, and colonic fermentation, the composition and changes of active components were determined, the in vitro bioactivity was evaluated, and the effects of the samples on human intestinal flora and their metabolites were investigated. The results revealed that the release of total polyphenol content (TPC) and total flavonoid content (TFC) were promoted after gastrointestinal digestion and colon fermentation, with the bioaccessibility of TPC and TFC increased by 103.28%–197.67% and 101.06%–144.01%, respectively. In addition, the antioxidant potency composite level significantly improved, and the inhibitory activity of cholinesterase was enhanced. Overall, G. elata has the ability to improve the intestinal flora structure, promote short chain fatty acid generation, and improve gut health. The obtained data are essential for the development of G. elata based functional foods and herbal formulations.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
