Abstract
Cention N (CN; Ivoclar Vivadent, Schaan, Liechtenstein), advertised as an alkasite, is a bioactive bulk-fill resin-based composite (BF-RBC) with alkaline fillers. This study evaluated the resin-dentin micro-tensile bond strength (μTBS) and cytotoxicity of CN. Methods: Flat dentin surfaces were obtained, bonded with a universal adhesive, and randomly distributed into two groups. CN (group I) and a flowable BF-RBC, namely, Tetric N-Flow Bulk Fill, Ivoclar Vivadent, Schaan, Liechtenstein (group II), were used. After thermocycling, bonded samples were sectioned into micro-beams for μTBS evaluation. Resin-based composite (RBC) discs with a thickness of 2 and 4 mm were tested on human gingival fibroblast cells (HGFCs). Cytotoxicity was assessed by cell viability and growth using AlamarBlue® (Biosource, Camarillo, CA, USA) over a seven-day period. Independent t-test was utilized to statistically analyze μTBS data, while one- and two-way analysis of variance (ANOVA) and Tukey’s post-hoc tests were utilized to analyze the cell viability data. Results: There was no statistically significant difference (p > 0.05) in the μTBS between the flowable BF-RBC and CN. For both materials, the HGFCs were viable, with constant growing over the seven-day period. Conclusion: CN provided a resin-dentin μTBS that was comparable to that provided by the flowable BF-RBC. Both materials showed acceptable cytotoxicity over the seven-day period at a thickness of both 2 and 4 mm.
Highlights
Resin-based composite (RBC) materials can be used efficiently to restore large-size posterior cavities [1,2]
Thirty beams were tested for each group
This study was designed to evaluate the resin-dentin μTBS and cytotoxicity of Cention N (CN) compared to a flowable bulk-fill resin-based composite (BF-RBC), given that this type of BF-RBC could provide superior curing compared to BF-RBCs of regular viscosity [11]
Summary
Resin-based composite (RBC) materials can be used efficiently to restore large-size posterior cavities [1,2]. Conventional RBC cannot be adequately light-cured in more than 2 mm increments [3]. Bulk-fill RBC (BF-RBC) materials allow the placement of posterior restorations in thick increments, making the restorative procedure less technique-sensitive [4]. Light-cured BF-RBC materials [5,6] and restorations [7] have been extensively evaluated in-vitro, showing mechanical properties comparable to those of conventional RBCs [8]. Whether BF-RBCs or conventional RBCs are used, the marginal integrity in-vitro is similar in posterior restorations [7,8].
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