Abstract
In Mexico, plasma drug quantitation is utilized to check dose titration, compliance, and toxicity in treatment with antiepileptic drugs like valproic acid (VPA), but without considering the pharmacokinetic principles due to the absence of clinical pharmacists in the Health System. This study analyzed the within-patient relationship between dosage and plasma VPA concentrations in different age groups, to evaluate the effect of enzyme-inducing co-medication, and to evaluate the efficiency of the m
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