Abstract
AimTo evaluate rupture pressures of tissue adhesives of cyanoacrylate (Omnex®) and fibrin (Evicel®), used as reinforcement in colonic suture from “ex vivo” swine. MethodsSurgical procedures were performed in the Surgical Technique Laboratory. From a division in segments of 10cm of descending colon and sigmoid colon from three “ex vivo” female swine, Landrace breed, which were resected in less than six hours after the slaughter time, 30 segments were selected, 10 of each animal. They were stored in saline solution 0.9% at 36°C, being randomly allocated in three groups (Control, Evicel and Omnex), each one containing 10 segments. ResultsThe lower and higher pressure values found in the groups Control, Evicel and Omnex were 36mmHg and 41mmHg, 70mmHg and 90mmHg, 90mmHg and 120mmHg, respectively. Containing statistical significance (p-value <0.0001) concerning the 2 to 2 comparisons (Control, Evicel and Omnex) with 95% trusting rate based on the application of the Turkey Method. ConclusionOne concludes that the use of tissue adhesives in anastomoses colonic in an experimental animal model of “ex vivo” swine increased the anastomoses rupture pressures. Among the tested adhesives, cyanoacrylate presented higher rupture pressure in relation to fibrin adhesive.
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