Evaluation of synergistic effect of polyglycine functionalized gold/iron doped silver iodide for colorimetric detection, photocatalysis, drug delivery and bactericidal applications

Abstract

The present study investigated the mercury ion detection by gold/iron doped Silver iodide supported on polyglycine (Au/Fe/AgI/PGA). The characterization of Au/Fe/AgI/PGA nanocomposites was conducted by using TEM, zeta/particle size analyzer, UV–visible absorption spectroscopy, FTIR and TGA. The Au/Fe/AgI/PGA depicted the λmax at 500 nm. The real water sample was investigated for the detection of mercury ion by using the prepared Au/Fe/AgI/PGA. The presence of other metal ions did not influence on interference for mercury ion detection. The photo-degradation of methyl orange in water by Au/Fe/AgI/PGA photocatalystwas evaluated. The degradation efficiency of Au/Fe/AgI/PGA was nearly 100% within 100 min, which was 1.7 and 1.3 times higher than of AgI and Au/Fe/AgI composites, respectively. Moreover, the antibacterial performance of the Au/Fe/AgI/PGA nanocomposites was studied against Legionella pneumophila and Mycobacterium tuberculosis. The Au/Fe/AgI/PGA as a carrier can be load and release doxorubicin (Dox) in a pH-sensitive pattern. The delivery performance of this carrier was investigated in vitro using MCF-7 cells.