Abstract

Aneurysm of the aortic root accompanied by aortic insufficiency is a common cardiovascular pathology. The optimal method of surgical treatment of this pathology is the reimplantation of the aortic valve into the aortic root synthetic prosthesis (David procedure). Currently, there is no comprehensive data on the influence of initial geometric parameters of the aortic root structures on the functioning of the reimplanted aortic valve after valve-preserving aortic root replacement. We have introduced a novel technique for creation and segmentation of a three-dimensional reconstruction of the aortic valve and root, which involves the sequential application of two computer-aided design environments: In Vesalius v 3.1.1 (Centro de Tecnologia da Informação Renato Archer (CTI)) and 3- Matic v. 13.0 (Materialise, Leuven, Belgium). The proposed method allows accurate measurement and evaluation of spatial parameters of the AV leaflets, fibrous ring, sinuses of Valsalva and sinotubular junction. The developed technique was used to evaluate the anatomical and functional features of the aortic valve in a 68-year-old patient who underwent David I procedure. Segmentation and measurement of the geometric parameters of the aortic root were performed before operation, as well as 18 months after surgical treatment. To assess the function of the reimplanted aortic valve during the long-term follow-up, a detailed echocardiographic assessment was used. Echocardiographic assessment included measuring volume and area of the regurgitation flow, the width of vena contracta, and the regurgitation fraction. The application of high-precision 3D reconstruction opens up additional opportunities in the field of surgical treatment of the aortic root and AV pathology: advantages in choosing an individual patient-oriented surgical tactics, parameters of the implanted surgical material and/or device, and in predicting long-term results of surgical treatment.

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