Abstract

The evaluation triiodothyronine, thyroxine, thyrotropin, c-reactive protein, interleukin-6 and tumor necrosis factorα in diabetic patients attending Abia State Teaching Hospital Aba, was carried out. Venous blood samples were collected from 150 participants who gave consent. This comprises 100 diabetic patients as test and 50 healthy subjects as control. The serum Triiodothyronine, thyroxine, thyrotropin was determined using Fincare™ quantitative assay method. Data from this study were analyzed using statistical package for the social sciences (SPSS). Result shows that thyroxine (8.97±1.28µg/dl), thyrotropin(2.08±0.85µiu/ml) respectively) (p<0.05 in each case). The serum triiodothyronine (0.89±0.38ng/ml), was lower in diabetic patients, compared with control (1.04±0.33ng/l) (p<0.05). From the findings, management of conditions related to cardiovascular disease, atherosclerotic disease, anemia and stress in diabetics may benefit patients if thyroid hormones are included as part of their routine laboratory investigations. Keywords: thyroid hormones, cardiovascular disease, diabetes mellitus, atherosclerotic disease

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