Abstract
The accuracy and comparative results of hemoglobin, hematocrit, red cell blood count, I 131 HSA blood volume, blood pressure, and pulse in one hundred human subjects with measured acute blood loss have been studied. These studies were carried out in each donor prior to, immediately after, at ten minutes, and at forty-eight hours after donation of 460 to 480 ml. of whole blood. Hemoglobin, hematocrit, and red blood cell counts all showed a small but persistent drop with a small standard deviation of 2 to 5 per cent. The hematocrit, on the average, had a higher point drop of 1.21 per cent at ten minutes after donation and 3.75 per cent at forty-eight hours after donation, possibly allowing this to be the better of these three mentioned studies for clinical evaluation purposes. The red blood cell volume, plasma volume, and whole blood volume determinations had similar standard deviations of 10 per cent throughout. The red blood cell volume showed an average decrease of 141 ml. at ten minutes after donation and 102 ml. at forty-eight hours. The blood volume showed a decrease of 259 ml. at the ten minute postdonation period and a hypervolemia of 183 ml. at the forty-eight hour period due to the increased plasma volume.
Published Version
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