Evaluation of Serum Calcitonin, Creatinine and Uric Acid in Ckd Complicated By Dysthyroidism

Abstract

This study evaluated the serum calcitonin, creatinine and uric acid levels in chronic kidney diseases (CKD) complicated by dysthyroidism. A total of 119 participants were recruited in this study, majority of who were males. This may likely be as a result of the bread winning role of men and hence are often economically empowered to seek health care. The higher proportion of males in this study could reflect a positive change in health seeking behavior of the male gender. Majority of the participants in this study were between the ages of 30 to 68 years with a median of 49 years. The high prevalence of CKD among this age group can be attributed to underlying pathologies such as hypertension, diabetes or both. Result from this study showed a significant increase (p ≤ 0.05) in serum calcitonin,TSH, creatinine and uric acid levels of CKD subjects when compared to the control and a significant decrease (p ≤ 0.05) was observed in serum T3 and T4 levels of CKD subjects were observed.T3 value showed significant decrease when the value of T3 gotten from stage 3,4 and 5 of CKD subjects were compared.