Evaluation of Role of Vitamin D in Grip Strength in Post-Menopausal Women with Fracture of Distal End Radius Treated with Closed Reduction and Percutaneous K-Wire Fixation

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Background: In the skin, under influence of ultraviolet radiation, 7-dehydrocholesterol is photoconverted to previtaminD3, which is converted to Vitamin D3 (cholecalciferol). In the serum, bound to a Vitamin D binding protein (VDBP), Vitamin D3 is transported to the liver, where it is hydroxylated to 25(OH)D3. In the kidneys, 25(OH)D3 is further metabolized to 1?,25-dihydroxyvitaminD3 [1,25(OH)D3], the biologically active form of Vitamin D . Vitamin D (Cholecalciferol) is known to contribute to muscular function. In the past decade, various cases of both young and elderly adults have been described, in whom prolonged vitamin D deficiency was associated with severe muscle weakness, often leading to marked disability that improved within several weeks of vitamin D supplementation. However, few studies have been conducted in which muscle strength was objectively quantified in relation to vitamin D status in elderly people. The purpose of this study was to determine whether the supplementation of vitamin D is associated with grip strength recovery in Post-Menopausal Women after a Distal End Radius fracture treated with Closed Reduction and Percutaneous K-wire fixation. Material and Methods: In this comparative study, Two groups were formed, First group as a case in which vitamin D was supplemented and second group as control in which Vitamin D was not supplemented, both the group had 25 number of post-menopausal women who had Vitamin D level between sufficient range (30-100ng/ml) and were treated with same mode of treatment (closed reduction and Percutaneous K-wire fixation) for Distal end radius fracture. Grip strength recovery (in %) was compared in both the group after a period of 6 months. Results: Final grip strength recovery of all patients came out to be 67%, out of which, in supplemented group it came out to be 73% while in non-supplemented group came out to be 60% with p value of statistically significance proving major difference in grip strength recovery