Evaluation of Regenerative Potential of Autologous Platelet Rich Fibrin in Horizontal Bone Defects in Chronic Periodontitis Patients

Abstract

Background and Aim In periodontal disease alveolar bone loss occurs mainly in two patterns - horizontal and vertical. Most commonly found among these is horizontal pattern of bone loss which received least attention while attempting regenerative periodontal therapy. Hence the objective of this research was to assess the ability of autologous Platelet Rich Fibrin PRF to promote periodontal regeneration in individuals with chronic periodontitis who have horizontal defects.Methods A total of 20 sites with horizontal bone loss were taken in five patients who had met the inclusion criteria. Informed consent was obtained from the patient. All the clinical as well as radiographic parameters were assessed. Open flap debridement with intramarrow penetration and placement of PRF was done for these patients and were followed up for nine months.Results All the patients were consistent with the follow up till nine months. Intergroup comparison of Probing Pocket Depth PPD and Clinical Attachment Level CAL showed significant difference with p lt0.05. Radiographic assessment also showed significant difference compared to baseline with p lt0.05. Conclusion The addition of PRF to horizontal periodontal defects has yielded noteworthy outcomes during a nine-month monitoring period.