Abstract
Background: Sepsis is a life - threatening organ dysfunction. Previous consensuses defined sepsis as infection with systemic inflammation response syndrome (SIRS). The new 2016 consensus selected SOFA and Quick SOFA instead of SIRS in diagnosing sepsis. 
 Objectives: 1. Describe clinical and subclinical characteristics of patients with sepsis. 2. Compare qSOFA and SIRS in the diagnosis and prognosis of the outcome of patients with sepsis. Subjects and method: Patients were diagnosed with sepsis based on the definition Sepsis - 2 (2001) or Sepsis - 3 (2016), treated at the Intensive Care Unit and the Department of Tropical Diseases, Hue Central Hospital. A prospective study.
 Results: There were 59 selected patients. The mean age was 60.22 ± 18.19 (28 - 90). Coagulation and cardiovascular dysfunction in patients with sepsis were the most common (61%), followed by kidneys (54%) and CNS (51%). Results of treatment: 44.1 % of patients had a septic shock; 28.8% died. In all patients, qSOFA ≥ 2 achieved rate was lower than SIRS ≥ 2 (72.9% compared to 98.3%). qSOFA0 had a high value in predicting ICU admission and had statistically significantly higher when compared to SIRS0. qSOFA0 had mean value in predicting in septic shock and had significantly higher when compared to SIRS0. qSOFA had a high value in predicting hospital mortality and had significantly higher when compared to SIR 0. 
 Conclusion: SIRS is more noted than qSOFA in patients with sepsis. qSOFA0 has higher value than SIRS 0 in predicting ICU admission and hospital mortality in patients with sepsis.
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