Abstract
Objective: The present study was aimed to identify the physicochemical data of shodhit guggul. Guggul is a gum-resin exudate from the plant Commiphora weightii (Arn.) Bhandari, belonging to Burseraceae family. In Ayurveda, guggul is always purified. This purification is known as Shodhan. Shodhan is a process by which guggul is made non-toxic, effective, suitable and fit for therapeutic purposes.Methods: The seven different shodhan dravya were used to prepare shodhit guggul. They were evaluated by performing physicochemical parameters including five different extractive value; total ash, acid insoluble, water soluble and sulphated ash value; pH, and loss on drying.Results: Analytical results of raw guggul showed total ash, acid insoluble ash, water soluble ash and sulphated ash value to 5.36±0.04%, 0.96±0.03%, 4.51±0.03 % and 8.40±0.04% respectively. These all values of each shodhit guggul were different. The extractive value of raw guggul was comparable with standard value while the extractive value of each shodhit guggul was totally different. The pH value of 1% w/v and 10% w/v aqueous solution of raw guggul was 6.44±0.18 though pH of each shodhit guggul was changed. The loss on drying of raw guggul was found to be 1.88±0.02%w/v, however, this value was different for each shodhit guggul.Conclusion: The present study revealed that the different shodhan process with specific shodhan dravya affects the physicochemical parameters. The analysis and comparison of the data showed the difference in the properties of seven shodhit guggul with respect to raw Guggul.
Highlights
IntroductionIn Ayurveda, drugs are obtained from plants, animals, and mineral origin
The traditional system of medicine is known as Ayurveda
The loss on drying of raw guggul was found to be 1.88±0.02%w/v, this value was different for each shodhit guggul
Summary
In Ayurveda, drugs are obtained from plants, animals, and mineral origin. These sources of drugs can be divided into poisonous and nonpoisonous class. The crude drugs obtained from these sources are generally possessed unwanted impurities and toxic substances, which can lead to harmful effect to human body [1]. Some medicinal plants are not safe to use as they can receive many toxic and harmful phytoconstituents in them. These phytoconstituents should be removed from the raw drugs. All these poisonous drugs should be purified and converted into suitable safe dosage forms for therapeutic use. In Ayurveda, this process is known as Shodhana [2, 3]
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