Evaluation of Physical Activity in Moroccan Postmenopausal Women with Osteoporotic Vertebral Fractures

Abstract

Introduction: The purpose of our study is to compare between physical activity (PA) in postmenopausal women with osteoporotic vertebral fractures and healthy women and to evaluate the relationship between PA and clinical and paraclinical parameters related to osteoporotic fracture. Methods: A case-control cross- sectional study, which included 128 postmenopausal women with densitometric osteoporosis as defined by Worlds Health Organization, with at least one radiological vertebral fracture. Physical activity was assessed by the International Physical Activity Questionnaire (IPAQ) short version with three items: vigorous, moderate activity and walking. Bone mineral density (BMD) and X-rays were performed in all patients. The controls were healthy women included in a randomized order in the general population, they were matched for age. Results: 128 patients with a mean age of 61.01± 8.40 years were included. 100 controls were included with a mean age of 60.61 ± 8.25 years. The patients had a median age of menopausal of 48.90 years [48-50], were osteoporotic in 49.2% and had osteopenia in 34.9%. 84 patients had a current back pain, and an average of three vertebral fracture with a median Genant score of 3.02[1-23]. There was no significant difference between the subjects of our study for total PA. However, vigorous-intensity activity and walking were significantly different between the two groups (p<0.05). Three independent factors were associated with a reduction of total physical activity: age, Genant score and physical function (for all p<0.05). In multivariate analysis, a significant association between total physical activity and age (p=0.003), trochanter BMD (p=0.01), Genant score (p=0.02) and physical function (2nd domain QUALEFFO) (p=0.01) persisted. Conclusion: In Moroccan postmenopausal women with osteoporotic vertebral fractures, PA is decreased with the severity of vertebral fractures and with the increasing age. Keywords: Physical activity, osteoporosis, vertebral fractures, postmenopausal women, Morocco