Abstract
ObjectiveThe aim of the study was to evaluate factors influencing quality of life (QOL) in Moroccan postmenopausal women with osteoporotic vertebral fracture assessed by the Arabic version of ECOS 16 questionnaire.Methods357 postmenopausal women were included in this study. The participants underwent bone mineral density (BMD) measurements by DXA of the lumbar spine and the total hip as well as X-ray examination of the thoraco-lumbar spine to identify subclinical vertebral fractures. Patients were asked to complete a questionnaire on clinical and sociodemographic parameters, and osteoporosis risk factors. The Arabic version of the ECOS16 (Assessment of health related quality of life in osteoporosis questionnaire) was used to assess quality of life.ResultsThe mean age was 58 ± 7.8 years, and the mean BMI was 28.3 ± 4.8 kg/m2. One hundred and eight women (30.1%) were osteoporotic and 46.7% had vertebral fractures. Most were categorized as Grade1 (75%). Three independent factors were associated with a poor quality of life: low educational level (p = 0,01), vertebral fracture (p = 0,03), and history of peripheral fracture (p = 0,006). Worse QOL was observed in the group with vertebral fracture in all domains except "pain": Physical functioning (p = 0,002); Fear of illness (p = 0,001); and Psychosocial functioning (p = 0,007). The number of fractures was a determinant of a low QOL, as indicated by an increased score in physical functioning (p = 0,01), fear of illness (p = 0,007), and total score (p = 0,01) after adjusting on age and educational level. Patients with higher Genant score had low QOL in these two domains too (p = 0,002; p = 0,001 respectively), and in the total score (p = 0,01) after adjusting on age and educational level.ConclusionOur current data showed that the quality of life assessed by the Arabic version of the ECOS 16 questionnaire is decreased in post menopausal women with prevalent vertebral fractures, with the increasing number and the severity of vertebral fractures.
Highlights
Osteoporosis is a growing public health concern among the elderly population, in postmenopausal women
This study shows that vertebral fractures, their number and the severity of deformities have a negative impact on quality of life (QOL)
This study has revealed that QOL in Moroccan postmenopausal women is impaired by the presence of vertebral fracture, by the increasing number and by the severity of vertebral fractures
Summary
Osteoporosis is a growing public health concern among the elderly population, in postmenopausal women. It's a debilitating chronic disease that can reduce the quality of life (QOL) in a variety of ways, including diminished physical and emotional functioning. The hallmark of osteoporosis, are commonly associated with back pain, kyphosis, and height loss. They can lead to a reduced mobility and may be very painful, which can limit everyday activities [1,2]. Theses factors have an important impact on the quality of life of osteoporotic patients. Measuring the quality of life in postmenopausal women is important. Generic measures are applicable to various diseases, and even to the general population. Disease-targeted measures can include items that are more closely related to the disease process, and can be more sensitive to the disease process when they are well designed
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