Abstract
Green Peas are tiny powerhouse of nourishment. They are rich in alpha-linolenic acid, flavonoids, carotenoids, phenolic acids, polphenols and pisumsaponins. The present study was employed to assess nootropic potential of Green Peas (Pisum sativum). Elevated Plus Maze model and Passive avoidance Paradigm served as Exteroceptive Behavioral models. Scopolamine and ethanol were used as amnesic agents. Pisum sativum (PS) in two different concentrations (2.5% w/w and 5% w/w) were administered with diet, for 15 successive days to mice. A decrease in transfer latency and increase in step down latency was observed. Further, green peas ameliorated memory deficits induced by scopolamine and ethanol in mice. PS produced significant increase in brain Glutathione levels, declined brain Malondialdehyde levels and reduced brain Acetylcholinesterase activity. Therefore, behavioral effects of PS would be worthwhile in management of cognitive dysfunctions.
Highlights
For all age groups cognition is important
Pisum sativum (PS) administered animals have shown significant (p
Memory deficits induced by Scopolamine and Ethanol were successfully reversed by pre-treatment of PS at 2.5 % w/w concentration
Summary
For all age groups cognition is important. Loss of memory affects most basic activities of daily living. Protein (Ali Khan and Young, 1973), fiber and micronutrients present in peas facilitate weight management. They possess antioxidant activity due to abundant flavonoids, carotenoids and polyphenols. Omega-3 fatty acids in the form of alpha-linolenic acid (ALA) are reported in peas (Andrzejewska et al, 2015). Presence of all such bioactive constituents in green peas makes them valuable for managing memory impairments. They could have protective role in age-related decline in Alzheimer’s disease
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