Abstract
The membranes of poly(γ-benzyl l-glutamate-co- l-glutamic acid) [P(BLG-LGA)] were prepared by saponification of poly(γ-benzyl l-glutamate) (PBLG) membranes. The permeation of two anticancer drugs, 5-fluoro-uracil (5-fu) and 2-hydroxyethyl-oxy-methyl-5-fluoro-uracil (2-HEOM-5-Fu), through these membranes was studied. The results showed a sharp increase in permeability of the copolymer membranes compared to the PBLG membranes.
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