Abstract
The use of the magnetic basket dissolution apparatus as a means of following the dissolution of tablets was studied. Several different formulations of pentobarbituric acid tablets were manufactured and used to illustrate the ability of the magnetic basket dissolution apparatus to differentiate between the dissolution of tablets with differences in particle size of active ingredients, in formulation, and in hardness. The magnetic basket dissolution apparatus was compared with the USP XVIII and Levy beaker methods for following dissolution. Log probability plots were used as a means of providing a quick and accurate dimension for analyzing dissolution data.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call