Abstract
The aim of the present study was to evaluate the locomotor and diuretic activ ities of both aqueous and alcoholic extracts of leaves of Epipremnum aureum ( AQEEa and ALEEa ) in experimental animals . Locomotor activity was evaluated by actophotometer and diuretic activity was evaluated using Lipschitz test model in rats . Preliminary ph ytochemical screening showed the presence of alkaloids, flavonoids, terpenoids and saponins . Intra peritoneal administration of AQEEa and ALEEa at doses 200mg / kg produced significant ( P< 0 . 01 ) CNS depression by reducing locomotor activity while it showed a significant ( P< 0 . 01 ) increase in the urine volume when compared to control . Thus, in conclusion the AQEEa and ALEEa have a significant CNS depression action by reducing locomotor and diuretic action in rats .
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