Abstract
Abstract The purpose of this study is to investigate the association between DNA damage and blood arsenic levels in individuals occupationally exposed to arsenic (As). 120 exposed individuals from silver mining plate workers were monitored in the way of DNA damage in blood lymphocytes using comet assay (single cell gel electrophoresis, SSGE). The DNA damage levels were measured by BAB Bs Comet Assay system and As levels were analyzed by the atomic absorption spectrometer system. The mean blood arsenic level was 17.03±10.85 µg/L. A statistically significant positive correlations were found between the arsenic levels and comet parameters (tail intensity, comet length and tail length) (p<0.01). Our results showed that exposure to arsenic may cause DNA damage in peripheral lymphocytes of Turkish silver mining plate workers. Key words: DNA damage; blood arsenic levels; Turkish workers; comet assay.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call