Abstract
The antioxidant and anticoagulant activities of polysaccharides isolated from the brown algae Dictyopteris polypodioides growing on the Lebanese coastNadine Karaki, Carine Sebaaly, Nathalie Chahine, Tarek Faour, Alexandre Zinchenko, Samar Rachidand Hussein Kanaan
Highlights
Fucoidan is a sulfated polysaccharide from brown algae and marine invertebrates (Klettner, 2016)
Seaweed used as raw material for fucoidan extraction was brown seaweed S. duplicatum which grows at a depth of 0.5– 10 m
Based on the results of the acute toxicity test using male mice and female mice using BPOM method No 7 in 2014, the results showed that LD50 for female mice and male mice was the same at 6.941 g/kg body weight (BW)
Summary
Fucoidan is a sulfated polysaccharide from brown algae and marine invertebrates (Klettner, 2016). It is a heteropolysaccharide that is mainly composed of fucose and sulfate esters. It comprises other monosaccharides like galactose, glucose, mannose, rhamnose, arabinose, xylose, uronic acid, proteins, and acetyl groups (Wang et al, 2019). Based on its polysaccharide structure, fucoidan has immune stimulator potential. The main sugar component of fucoidan that has an immunomodulatory function is L-fucose. It has been found to have various bioactivities, including antioxidant, anti-inflammatory, immunoregulatory (Sun et al, 2018; Zhang et al, 2015), antiviral, antitumor, antidiabetic, and antihepatic injury activities (Peng et al, 2019)
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