Evaluation of changes in kidney masses within 15 years

Abstract

Objective: kidney cancer has a frequency of 3% in all cancers and this frequence has increased recently. We tried to investigate the prevalence, stage and type of renal tumors within 15 years in Mashhad. Methods & Materials: In this cross-sectional study, the pathologie of patients undergone nephrectomy due to tumor in previous (2001-2002) and recent(2016-2017)years in Imam Reza Hospital in Mashhad, were examined. All records of both groups were reviewed including demographic information and mass informations such as number, size and type of pathology. Results: Among 145 patients, 45 (31%) were prevoiusly registered in 2001-2002 and 100 (69%) were recently registered in 2016-2017. 71% of new cases and 55.56% of prevoius cases were male and both groups were in second group. There was no significant differences in the frequency distribution of gender (P = 0.07), disease grade (P = 0.75), mass location (P = 0.24), resection type (P = 0.89), lymphovascular invasion (P = 0.74) and extracapsular (P = 0.84) between old and new cases. The final diagnosis in 95% of new cases and 84.4% of old cases was renal cell carcinoma (RCC) and there was a significant difference in the frequency distribution of the final diagnosis between old and new cases (P = 0.02). Conclusion: This study shows the general pattern and increasing incidence of RCC in Mashhad, which requires further studies to investigate the etiology and risk factors and even eliminate them if possible.