Abstract

Background: Cardiovascular disease (CVD) is the leading cause of mortality among men and women around the world. The aim of this study was to investigate major cardiovascular risk factors in women living in the Tabriz petrochemical region, Iran during spring 2017.Methods: In this cross-sectional study, a sample of 152 women aged 30-55 years was selected from who attended health center in Tabriz, Iran. Anthropometric measurements, blood pressure,daily dietary intakes and fasting serum lipid profile, oxidized LDL (ox-LDL) and high sensitivity C-reactive protein (hs-CRP) were evaluated.Results: The prevalence of overweight, general and abdominal obesity (based on Body mass index [BMI] and waist circumference [WC]) was 34.2%, 52.6%, and 73.7%, respectively. Eleven point two percent and 4.6% of women had pre-hypertension based on systolic blood pressure (SBP)and diastolic blood pressure (DBP). High serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and low high-density lipoprotein cholesterol (HDL-C)were determined in 32.5%, 25.7%, 17.8% and 56.6% of subjects, respectively. The median of serum ox-LDL concentration was 3181.5 ng/L. Sixty-five point eight percent of participants hadhigh hs-CRP levels. In the multiple-adjusted quintile regression analysis, significant relationships were found between serum ox-LDL and age (B = 96.7, P = 0.003) and between serum hs-CRP with diastolic blood pressure (B = 0.1, P = 0.083) and TG (B = 0.01, P = 0.088).Conclusion: The high prevalence of cardiovascular risk factors in the studied women warrants more public health attention. The results also suggest that aging was associated with high serumox-LDL and increased serum hs-CRP levels, which may reflect enhanced DBP and serum TG.

Highlights

  • Health promotion is one of the leading and high-priority dimensions of public health.[1]

  • Seventy-three percent of subjects had abdominal obesity based on Waist circumference (WC) category and 79.4% based on Waist-hip ratio (WHR) classification

  • Frequency of subjects with pre-hypertension were 11.2% and 4.6% based on systolic blood pressure (SBP) and diastolic blood pressure (DBP), respectively

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Summary

Introduction

Health promotion is one of the leading and high-priority dimensions of public health.[1] Cardiovascular disease (CVD) is one of the most important health problems and the leading cause of mortality among men and women around the world. It is the main reason for disability and most predictable non-communicable diseases.[2,3] According to the World Health Organization (WHO), there are 17.5 million deaths annually due to CVD in the world and nearly 30% of all deaths are due to these diseases.[4] CVD mortality rate was reported to be 203 and 331 per 100 000 person-years in women and men of Isfahan, Najafabad and Arak, Iran.[5] In the study by Azizi et al 78% of men and 80% of women aged ≥30 years in Tehran, Iran presented at least one CVD risk factor.[6]. The results suggest that aging was associated with high serum ox-LDL and increased serum hs-CRP levels, which may reflect enhanced DBP and serum TG

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