Abstract
The purpose of this study is to analyze the independent clinical, laboratory, dialysis factors between a disease-specific score for cardiac risk stratification and the Quality of life (QOL) application in hemodialysis (HD) patients. A total of 43 end-stage renal disease patients (female 17 and male 26) on regular HD were included. They were clinically stable with a mean Kt/V (Daugirdas) 1.76±0.41 and mean dialysis 7.4±0.94 years. Patients answered the Kidney Disease Quality of Life questionnaire short form (KDQOL-SF) which includes the physical and mental health component (PHC, MHC). Application of a previously validated cardiac risk score (CRS) using cardiac history (A), dialysis duration (B), body mass index (C) and serum phosphate (D) multiplied by various hazards ratio (HR) was also investigated retrospectively. CRS (A+B+C+D)< 50 allocated low risk, and CRS≥50 stands for high risk of future cardiac events. The impact of various factors on CRS and KDQOL-SF was estimated by multivariate analysis using SPSS 10.0 depending on variables characteristics. Most of the KDQOL-SF scores specific for dialysis significantly correlated with Hct, albumin, electrolytes, age, dose of HD and social support (P
Highlights
Materials and MethodsDespite the flashing advances in medical science investigation and clinical therapy, population of end-stage renal disease (ESRD) with subsequent renal replacement therapy patients is still growing annually [1]
health-related QOL (HRQOL) dimension scores of KDQOL-SFTM questionnaire (Table 1) obtained from the HD patients is significantly (P< 0.001) lower as comparing with the scores obtained from the normal control in Taiwanese population (Figure 1)
One of the HD efficiency data was significantly related to cognitive function and quality of social interaction dimensions in KDQOL
Summary
Materials and MethodsDespite the flashing advances in medical science investigation and clinical therapy, population of end-stage renal disease (ESRD) with subsequent renal replacement therapy patients is still growing annually [1]. HD patients can have impaired daily functioning because of their primary kidney disease and comorbid conditions [7] Among these efforts, the role of assessments of health-related QOL (HRQOL) by the application of generic and specific measures that are used to examine which dimensions or areas in patients’ life are impaired and necessitate an appropriate intervention is important [8,9]. The aim of this study was to analyze the association between independent clinical, laboratory, dialysis factors and self-efficacy of the QOL with HD treatment outcome which will be compared with a validated disease-specific score for cardiac risk stratification [12,13,14] and the QOL application in HD patients [15]
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