Evaluation of CANON SD HS 100 OCT : Reproducibility of macular ganglion cell complex (GCC) thickness measurement in normal, hypertensive and glaucomatous eyes

Abstract

AbstractPurpose To evaluate intra‐ and interobserver reproducibility of macular GCC thickness measurement by automated segmentation on CANON SD HS 100 OCT (Japan) in normal (N), hypertensive (OHT) and glaucomatous eyes.Methods A total of 179 eyes of 93 patients were included: 88 N, 26 OHT and 65 glaucoma. All patients underwent a complete ophthalmologic exam, pachymetry and 24‐2 automated perimetry (HFA SITA Standard). Each of two observers performed three times macular imaging with SD HS 100 OCT. Acquisitions were analyzed with Glaucoma 3D mode which estimated the macular GCC thickness in global, upper and lower macular parts and in eight separate areas. Reproducibility was assessed by intraclasss correlation coefficient (ICC), coefficient of variation (CV) and test‐retest variability (TRTV) calculated as 1.96 times the standard deviation.Results Mean GCC thickness was respectively 92.6µm, 88.7µm, 77.4µm in N, OHT and glaucomatous eyes. In all groups, intra‐ and interobserver reproducibility was respectively ranged for ICC from 96 to 99.7% and from 84.5 to 99.7%, for CV from 0.44 to 2% and from 0.37 to 1.1% and for TRTV from 0.75 to 2.62 µm and from 0.59 to 1.47µm. Reproducibility is significantly better in N and OHT group than in glaucoma group (p<0.001).Conclusion Reproducibility of GCC thickness measurements using the new OCT SD HS 100 is high. These results might be related to a high axial resolution (3µm). They underline reliability data for analyze of GCC.