Abstract
Evaluation Of Bcl-2 Gene Translocation In NSCLC Lung Cancer Based On Age And Sex Seg
Highlights
All excised slides were examined by a pathologist using a light microscope and Non-small cell lung carcinoma (NSCLC) lung cancer specimens were confirmed by a pathologist at this stage
The positive mcr samples were banded on 1% agarose at 630 bp region and the icr positive samples were banded on 1% agarose at 135 bp region
Because the incidence of NSCLC is directly related to age, the incidence of cancer increases with increasing age of the population
Summary
The cause of most cancers is the accumulation of mutations in somatic cells. Cell death has a genetic basis and does not occur if this genetic system is disrupted [1].Cell death is part of the growth program in animal cells. The cause of most cancers is the accumulation of mutations in somatic cells. Cell death has a genetic basis and does not occur if this genetic system is disrupted [1]. Cell death is part of the growth program in animal cells. Planned cell death (apoptosis) is important to avoid cancer. All the protein’s family found in B-cell lymphoma has a common similar region called the second Bcl-2 identical. These regions are involved in regulating the release of cytochrome C from mitochondria. Cytochrome C release is a common event in apoptosis. Cytosolic cytochrome C with binding to apoptotic factors such as Factor-1 (Apaf-1, Apoptotic protease activating factor 1), dATP/ ATP and procaspase 9 makes the complex of apoptosomes [2]
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