Evaluation of Atropine-Xylazine as a Sedative in Buffalo Calves (Bubalus bubalis)

Abstract

Twelve experimental trials were undertaken on clinically healthy male buffalo calves. Atropine was administered @ 0.04 mg/kg, IM and xylazine was administered @ 0.04 mg/kg, IM. Following atropine-xylazine administration, a decrease in spontaneous activity was seen in all the animals. Lowering of head was observed in three animals. Haemoglobin reduced significantly at 15 minute after xylazine administration. A significant reduction in mean arterial pressure (MAP) was also seen at 30 and 45 minute after xylazine administration. The pulse pressure increased significantly after 5 minute of xylazine administration. The central venous pressure (CVP) increased significantly at 30 minute and 45 minute of xylazine administration.