Abstract

Twelve experimental trials were undertaken on clinically healthy male buffalo calves. Glycopyrrolate was administered @ 0.01 mg/kg, IM and xylazine was given @ 0.04 mg/kg, IM. Glycopyrrolate-xylazine combination produced ataxia in all the animals along with a decrease in spontaneous activity. Four animals went to sternal recumbency. Mild cutaneous analgesia was seen in all the animals. A significant increase in heart rate, MAP and CVP along with a significant reduction in pulse pressure was noticed.

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