Abstract
Plant phytonutrients have been harnessed for their various curative properties both in vitro and in vivo. In this study African black velvet tamarind (ABVT) fruit pulp was evaluated for it antioxidant potentials using chloroform and hexane fractions through different antioxidant parameters. In the results; total phenolic contents quantified in mg GAE/dried sample in chloroform and hexane extracts were; 14.57 ±5.85 and 9.78 ±4.61, total flavonoid contents in chloroform and hexane extracts as; 48.58 ±0.00 and 27.35 ±0.00 while the FRAP (µg AAE.g-1 dried sample) was lower in chloroform (298.10 ±0.00) than hexane extracts (1029.81 ±0.00). More also, ability of varied concentrations of the extracts (with their IC50) to cause inhibition against Fe2+-induced MDA that was determined by TBARS in rat's brain and liver tissue homogenates, Fe2+-chelating ability and other antioxidant assays, showed an appreciable significant (p <0.05) difference. The various antioxidant properties showed by ABVT has indicated that, if the pulp is incorporated in diet, it could serve as an alternative in managing various ROS-induced degenerative ailments as it has been clearly demonstrated in the protection of brain and liver homogenates from Fe2+-induced oxidative stress.
Highlights
Oxidative stress induction through reactive oxygen species (ROS) has been studied explicitly and the roles play in promoting different diseases both in humans and animals directly or otherwise as a results of either a decrease in natural cellular antioxidant ability or an increased oxidants level cannot be over emphasized (Afolabi and Oloyede, 2014a)
The various antioxidant properties showed by African black velvet tamarind (ABVT) has indicated that, if the pulp is incorporated in diet, it could serve as an alternative in managing various ROS-induced degenerative ailments as it has been clearly demonstrated in the protection of brain and liver homogenates from Fe2+-induced oxidative stress
Plants are naturally endowed with natural antioxidants that exhibit cell’s defensive mechanisms through scavenging the reactive oxygen species (ROS), with protective effects against degenerative diseases in humans (Shalaby and Shanab, 2013). They exhibit antioxidant activities through electron donation and thereby neutralizing the damaging effects of free radicals, whose formation is associated with aerobic cells normal natural metabolic processes (Amic et al, 2003)
Summary
Oxidative stress induction through reactive oxygen species (ROS) has been studied explicitly and the roles play in promoting different diseases both in humans and animals directly or otherwise as a results of either a decrease in natural cellular antioxidant ability or an increased oxidants level cannot be over emphasized (Afolabi and Oloyede, 2014a). Ability of varied concentrations of the extracts (with their IC50) to cause inhibition against Fe2+-induced MDA that was determined by TBARS in rat’s brain and liver tissue homogenates, Fe2+-chelating ability and other antioxidant assays, showed an appreciable significant (p
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