Abstract
Objective: Discovering new antibacterial drugs with high efficacy and low toxicity from medicinal plants has received increasing attention worldwide. The aim of this study was to investigate the antimicrobial activity of ethanolic extract of Alocasia cordfolia rhizomes (ACRE). Methods: S.aureus, E.coli and C.albicans were selected as the tested microorganisms. The diameter of the inhibition zone was determined by the disc diffusion method, and MIC and MBC were measured using the broth microdilution method. Results: The diameter of the inhibition zone, MIC and MBC values of ACRE against S. aureus were 7.67±0.58 mm, 160 μg/μL and 320 μg/μL, and that of ACRE against C.albicans were 8.33±1.15 mm, 80 μg/μL and 160 μg/μL, respectively. However, ACRE did not show antimicrobial activity against E. coli. Conclusion: ACRE may be a potentially promising natural antimicrobial product, and further studies are needed to identify the specific active compounds present in this extract and to elucidate their antimicrobial mechanisms.
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