Abstract
The present study was aimed to evaluate the anti-diabetic activity of isolated compounds from aerial parts of Ficus bengalensis in alloxan induced diabetic rats. Diabetic wistar albino rats were treated with standard drug Glibenclamide and prepared drug extract in 150 mg/kg. Hypoglycemic effect was evaluated in these rats and the efficacy of isolated compounds was administered in alloxan induced diabetic rats. At the end of study period blood glucose level were statistically analyzed based on the results. Isolated fractions produced a significant reduction in blood glucose level when compared with non-treated diabetic rats. So the present research work was confirmed that the isolated compounds possess hypoglycemic effect significantly.
 Keywords: Ficus begalensis, antidiabetic, allaxon induced, Diabetes mellitus.
Highlights
Before the advent of insulin, diabetes was treated with plant medicines
The present study was aimed to evaluate the anti-diabetic activity of isolated compounds from aerial parts of Ficus bengalensis in alloxan induced diabetic rats
Hypoglycemic effect was evaluated in these rats and the efficacy of isolated compounds was administered in alloxan induced diabetic rats
Summary
Before the advent of insulin, diabetes was treated with plant medicines. The plant kingdom represents a largely unexplored reservoir of biologically active compounds as drugs, and as unique templates that could serve as a starting point for synthetic analogs and an interesting tool that can be applied for a better understanding of biological processes. Folkloric uses are supported by a long history of human experience[1]. Numerous biologically active plants are discovered by evaluation of ethno-pharmacological data, and these plants may offer the local population immediately accessible therapeutic products. In the present study, investigated the antidiabetic properties of ethanolic extracts and chloroform fraction of aerial parts of Ficus bengalensis Linn on normal and alloxan induced diabetic rats
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