Abstract
Portulaca quadrifidaL. (PQ) having the phytochemicals like Alkaloids, flavonoids, Saponins, tannins, glycosides, carbohydrates, aminoacids, triterpenoids. The present study was performed to evaluate the antioxidant and anti-inflammatory activities by using acetic acid induced vascular permeability model in mice & acetic acid induced colitis in rats significantly. PQ (100 mg/kg, p.o.) presented a significant anti-inflammatory activity towards acetic acid induced vascular permeability model in mice in comparison to Diclofenac sodium(10 mg/kg, s.c.) and acetic acid induced colitis in rats in comparison to 5-ASA. Our findings suggest that, PQ contains potential antioxidant and anti-inflammatory compounds which will aid us to conduct bioactivity guided isolation & characterization of leading compounds in due course.
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