Evaluation of Anemia in Thyroid Dysfunctions Anemia in Thyroid Dysfunctions: Retrospective Cross-Sectional Study

Abstract

Objective: Evaluation of Anemia in Thyroid Dysfunctions Anemia in Thyroid. Materials and Methods: The study analyzed 145 medical records of patients diagnosed with thyroid disorders (102 women and 43 men), receiving care between January 2011 and February 2018 at the University Hospital of Florianópolis, Brazil, selected with thyroid disorder ICD. Results: Obtained by analyzing the medical records and assessing laboratory parameters: thyroid-stimulating hormone (TSH), free thyroxine (FT4), mean corpuscular volume (MCV), red blood cell distribution width (RDW), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), hemoglobin values (Hb), red blood cell count (RBC), hematocrit values (Hct), cytomorphological erythrocyte changes, serum iron, and ferritin. Most patients were diagnosed with primary hypothyroidism, followed by primary hyperthyroidism. Hemoglobin values were present in 95.9% of patients with hypothyroidism and 89.6% of those with hyperthyroidism. Patients whose hemoglobin values were below 12 (for women) or 13 g/dl (for men) were classified as anemic. The frequency of anemia was 41.0% of patients – 76.3% had some type of hypothyroidism, while 29.7% had some type of hyperthyroidism. Conclusion: Normocytic and normochromic anemia was observed in both thyroid disorders. In hyperthyroidism, values neared microcytosis. Red blood cell counts were statistically different between males with hypothyroidism and hyperthyroidism. Hypothyroidism was statistically related to diabetes, systemic arterial hypertension, and cardiovascular diseases.