Evaluation of aerobic capacity and muscle function in a case series of patients with relapsing polychondritis

Abstract

Background: To evaluate aerobic capacity and muscle function in patients with Relapsing Polychondritis (RP). Methods: A cross-sectional single center study evaluated seven women with RP (McAdam criteria) that were compared to seven healthy control individuals matched for age, gender, and body mass index. Both groups performed a treadmill-graded maximal exercise. Aerobic capacity was assessed by peak oxygen uptake (VO2 peak), time at anaerobic Ventilatory Threshold (VAT) and Respiratory Compensation Point (RCP) and time-to-exhaustion. Muscle function was evaluated through the sit-to-stand and the timed up-and-go test.