Abstract
Background: The benefit of use of prophylactic antibiotic in mesh inguinal hernia repair needs evaluation in view of emergence of resistant micro-organisms with indiscriminate use of antibiotics and also to avoid unnecessary expenditure.Methods: 100 patients of primary inguinal hernia, fulfilling inclusion criteria, were recruited in a prospective, randomized, double blind study where single dose of prophylactic antibiotic half hour prior to mesh repair surgery was administered to 50 patients in study group and routine antibiotics to remaining 50 in control group. Follow up was done for any evidence of infection till one month after the surgery.Results: The incidence of infection in both the groups was analyzed. Prophylactic antibiotic group reported to have an infection rate of 12% as compared to 10% in control group Incidence of infection in both groups was 2% at time of discharge and 0% after one week, at the time of suture removal. Two week after discharge 6% in study and 4% in control groups had infection. After one month of surgery, incidence of infection was 4% in both prophylactic antibiotic group and control group. None of the patients required mesh removal and results was statistically similar in both groups.Conclusions: The use of prophylactic antibiotic in our study was seen to be as effective as routine preoperative and postoperative antibiotics and should be recommended as it reduces the cost burden to the patient significantly and also prevents development of bacterial resistance to drugs.
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