Abstract
To evaluate the efficacy of a simple low-cost intervention to empower people with chronic kidney disease (CKD) to reduce their dietary salt intake. A randomized controlled trial in primary and secondary care comparing the OxSalt care bundle intervention versus standard care for 1 month. Participants were people with CKD and an eGFR (estimated glomerular filtration rate) greater than 20 ml/min/1.73m2 and were recruited from primary and secondary care. The primary outcome was a reduction in dietary salt intake, assessed by 24-hour urinary sodium excretion, after 1 month of the intervention. 201 participants were recruited. Dietary salt intake, as assessed from 24-hour urine sodium excretion, fell by 1.9 (±2.9) grams per day in the intervention group compared to 0.4 (±2.7) grams per day in the control group (p < 0.001). Salt intake was still reduced to a lesser extent over the following year in the intervention group. A short, low-cost, easily-delivered intervention empowers people with CKD to reduce their dietary salt intake.Trial registrationClinicalTrials.gov NCT01552317.
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