Abstract
The preparation of a new chiral stationary phase (CSP) based on mixed immobilized human serum albumin (HSA) and α 1-acid glycoprotein (AGP) is reported. Enantiomeric separations of basic, acidic and neutral compounds on this AGP-HSA CSP were compared to those obtained on a HSA CSP and on a AGP CSP. The results show that the new CSP has a wider range of applications than the initial CSPs. For two compounds, the enantioselectivity on the mixed CSP was higher than on the HSA CSP.
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