Abstract
Background: Quality may be described as the character that determines the degree of excellence. A good quality medication is anything that meets the product specifications, can be purchased safely, and can be used confidently for the purpose for which it was designed.To obtain a high quality medication, the manufacturing process for producing a drug should have quality integrated into it. Analytical chemistry is the discipline that seeks ever better methods of assessing the chemical composition of natural and manmade materials.
 Aims and Objective: Evaluation and validation of carvedilol in bulk and pharmaceutical dosage forms.
 Material and Methods: preparation of standard stock solution and preparation of sample solution as per standard protocol.
 Result: In the RP-HPLC method, a wavelength of 242 nm was retained and the retention time was found to be 2.9 with optimised conditions. Carvedilol showed linearity in the range of 15.62 -93.75µg/ml. where the peak shape was symmetrical and a good correlation coefficient value was obtained.
 Conclusion: RP-HPLC, HPTLC, UV spectroscopy were found to be sensitive, precise, and accurate. However these three methods can be used for the routine analysis of carvedilol from formulation.
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