Abstract

Introduction: Chronic kidney disease (CKD) in advanced stages leads to some changes in lifestyle, health status, and personal functioning and consequently affects the patients’ quality of life. Objectives: Given the high prevalence of CKD in the country, this study aimed to determine quality of life and its related factors in this group of patients. Since there has been low focus on quality of life in pre-dialysis stage, this study compared the two groups of pre-dialysis and hemodialysis patients regarding quality of life. Patients and Methods: This descriptive analytical research was conducted as a cross-sectional study. Using convenience sampling method, we selected a total of 60 kidney failure patients in pre-dialysis stage that referred to nephrology clinics in Semnan and 60 hemodialysis patients who referred to the dialysis center of Kosar hospital in Semnan. Using SF-36 questionnaire and a demographic form, the required data was collected via interviews. Results: The results showed that the majority of patients had a moderate quality of life. Concerning demographic variables, quality of life had a significant relationship with age, gender, marital status, number of children, employment status, education level, income level, hemoglobin, underlying disease, duration of disease, and duration of dialysis. Moreover, patients in pre-dialysis stage had a better score than hemodialysis patients regarding the overall quality of life (P≤0.05). Conclusion: This study showed, a design a framework for care services provided by medical staffs and supports provided by insurance organizations and other institutions is necessary. The framework must help to improve quality of life of patients and prevent the deterioration of quality of life in advanced stages of the disease.

Highlights

  • Chronic kidney disease (CKD) in advanced stages leads to some changes in lifestyle, health status, and personal functioning and affects the patients’ quality of life

  • The present study aimed to investigate quality of life of patients with CKD in Semnan through using SF-36 questionnaire at different stages of disease

  • End stage CKD patients on hemodialysis are saved from certain death, apparently during the disease progress they are affected by a wide range of physical, psychological, social, and economic problems which in turn will affect their quality of life [21]

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Summary

Introduction

Chronic kidney disease (CKD) in advanced stages leads to some changes in lifestyle, health status, and personal functioning and affects the patients’ quality of life. Objectives: Given the high prevalence of CKD in the country, this study aimed to determine quality of life and its related factors in this group of patients. Since there has been low focus on quality of life in pre-dialysis stage, this study compared the two groups of pre-dialysis and hemodialysis patients regarding quality of life. We selected a total of 60 kidney failure patients in pre-dialysis stage that referred to nephrology clinics in Semnan and 60 hemodialysis patients who referred to the dialysis center of Kosar hospital in Semnan. The clinical and laboratory signs are highlighted in stage 3 and 4

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