Abstract
Obesity contributes to the onset and progression of osteoarthritis. This study assesses the influence of baseline body mass index (BMI) and baseline knee pain on improvements observed in patients undertaking a community-based weight loss program for knee osteoarthritis. This study is a retrospective analysis of data from 9004 patients who took part in the Osteoarthritis Healthy Weight For Life program between January 2014 and July2022. The greater the weight loss achieved, the greater the improvement in knee pain and function, with baseline weight having no effect on the magnitude of the outcome. All patients with a starting Knee Injury andOsteoarthritis Outcome Score of <75 experienced significant improvement in their symptoms. Patients with more severe starting pain saw greater improvements. Baseline BMI has no effect on the amount of weight loss required to produce a meaningful improvement in osteoarthritis symptoms. Patients with more severe baseline knee pain see more improvement than those with milder symptoms for the same weight loss.
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