Evaluating the Inter Relationship between Obesity and Diabetes Mellitus Type 2: A Clinical Pilot Study

Abstract

Purpose: This study aims to investigate the effect of anthropometric parameters and clinical indexes on a sample of diabetic patients. Material and Methods: 440 patients with Type 2 diabetes (T2D), with an average age of 49.9 years, who were selected from a sample of 2.500 cases. Entry criteria for the group were the long-term follow-up period of patients and the repeatability of lab tests. Results: A strong effect was observed between Body Mass Index (BMI) and hyperglycemia. The frequency of T2D occurrence, was higher in overweight patients (>25 kg/m²) than in those with normal weight (<25 kg/m²). The mean BMI of newly diagnosed diabetic patients was 30.2 Kg/m². There was found a dependence between BMI and sex with the occurrence of cholelithiasis-cholecystitis, with a higher incidence in the class of obese and women. People with normal weight were found to have T2D at a younger age than the other BMI classes that did not differ from each other. Women show higher glucose concentrations than men with normal body weight. At the same BMI class, blood glucose is higher in women than in overweight class. In men no change in glucose was observed at the different BMI classes. The transition of hemoglobin (HbA1c) from step 2 (>7%) to step 1 (<7%) causes a triglyceride concentration reduction of 14.5%. BMI was recorded as the third factor correlated with hyperglycemia, after predisposition and hyperlipidemia and before diastolic blood pressure and age. Conclusions: At the ascertainment of the newly diagnosed T2D, the presence or not of obesity, determined of BMI, does not affect blood glucose levels in men. In women the normal BMI levels are not deterrent factors of high glucose values, nor age, regardless of gender. BMI is classified as third correlation factor of highglucose values in newly diagnosed diabetics.