Abstract
Objective: To evaluate the patient perception of the ease of use associated with Genotropin Go Quick disposable injection pen for the treatment of pediatric short stature and growth hormone deficiency. Methods: This is a descriptive study including patients between 2-18 years of age undergoing GH treatment using Genotropin Go Quick for a minimum of 6 months. Data were collected through a personal interview in pediatric endocrinology clinics and questions were answered by those primarily administering the medication. Subjects were asked to grade the difficulty of each of the 9 steps involved in setting up Genotropin Go Quick pen at the start of treatment, 3 months, and 6 months after on a scale of very easy, somewhat easy, neutral, challenging, or difficult. Results: A total of 310 patients were included of whom 48.4% were female. At the start of treatment, 28.8% found its use easy whereas 71.6% found it difficult. After 3 and 6 months, 81.9% and 86.8% found its use to be easy whereas 14.8% and 12.3% still found it difficult, respectively. The hardest steps identified were premixing of Genotropin solution and removal of trapped air, whereas the easiest steps were disposal of the pen or its associated parts, attaching the needle guard, and injecting the dose. 99% found storing Genotropin Go Quick and 97% found transporting it while traveling to be very easy. Conclusion: Ease of use of an injection device is essential to ensure optimal treatment outcome and duration, minimal metabolic consequences, and avoid unnecessary high treatment costs. The majority perceived Genotropin Go Quick as difficult to use at the start of treatment yet easy after 3 months. The two most challenging steps were identified as premixing the solution and removing trapped air. Genotropin Go Quick almost unanimously was considered easy to store and transport when traveling.
Published Version
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