Abstract
Abstract Introduction: The escalating resistance of bacterial strains to conventional antimicrobial agents necessitates the exploration of alternative natural remedies. This study investigates the anti-bacterial efficacy of Triphala and Aloe Vera extracts, individually and in varying proportions, against Enterococcus fecalis compared to established chemical agents, specifically 0.5% and 3% sodium hypochlorite (NaOCl). Materials and Methods: Standard strains of E. Coli were inoculated in the Mueller–Hinton agar plates incubated at 37°C for 24 h, using the agar well diffusion method with irrigants categorised as Group I: Triphala extract, Group II: Aloe vera extract, Group III: Triphala and aloe vera extract in 1:2 combination, Group IV: NaOCl in 0.5% concentration and Group V: NaOCl in 3% concentration. Data were analysed using ANOVA and post hoc tests, with significance set at P < 0.05. Results: The results demonstrated significant anti-bacterial activity of both natural products, with varying effects based on their combination ratios. Combination therapies using Triphala and Aloe Vera produced enhanced anti-bacterial effects compared to individual applications against E. fecalis bacterial strains. The results were not statistically significant, indicating herbal irrigants performed equivalently as compared to both the concentrations of NaOCl used in this research study. Conclusion: Combinations of natural products in this study exhibit significant anti-bacterial activity, suggesting their potential role in further applications for disinfection and endodontic treatments which needs to be corroborated with further clinical studies.
Published Version
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