Etioloy and potential mechanism of cerebral infarction post severe traumatic brain injury

Abstract

Objective To investigate the clinical characteristics,risk factors and potential mechanism of cerebral infarction post severe traumatic brain injury(TBI).Method Clinical records of 24 patients suffering cerebral infarction and 46 patients without cerebral infarction after severe TBI were reviewed retrospectively.Results patients with cerebral infarction got a survival rate at 58％,lower than patients without cerebral infarction (83％).The maximal body temperature (38.1 ± 0.8) ℃ in the first 24hrs,incidence of coagulating dysfunction (75％) and middle cerebral artery spasm(75％) were much higher in infarction group than the non-infarction group (P ＜ 0.05).Conclusion Cerebral infarction exerts a tremendous influence on the prognosis of severe TBI.Cerebral vessel spasm,devastation and compression of the vessel structure are the high risk factors for cerebral infarction after severe TBI. Key words: Brain trauma; Brain infarction; Cerebral vasospasm; High risk factors