Abstract

Background: Women with recurrent pregnancy loss (∃3 consecutive) are usually evaluated for noncytogenetic causes, such as uterine anomalies, antiphospholipid antibody syndrome (APAS), and other thrombophilias, although many remain unexplained. We feel that the evaluation of recurrent pregnancy loss is incomplete without embryonic genetic evaluation and suspect that recurrent pregnancy loss (RPL) in women over age 35 (AMA) is more frequently due to age-related aneuploidy than underlying thrombophilias or abnormalities of the uterine cavity.

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