Abstract
Senna alata is a medicinal herb of Leguminosae family. It is distributed in the tropical and humid regions. The plant is traditionally used in the treatment of typhoid, diabetes, malaria, asthma, ringworms, tinea infections, scabies, blotch, herpes, and eczema. The review is aimed at unveiling the ethnobotanical description and pharmacological activities of S. alata. Different parts of the plant are reported in folk medicine as therapeutic substances for remediation of diverse diseases and infections. The extracts and isolated compounds displayed pronounced pharmacological activities. Display of antibacterial, antioxidant, antifungal, dermatophytic, anticancer, hepatoprotective, antilipogenic, anticonvulsant, antidiabetic, antihyperlipidemic, antimalarial, anthelmintic, and antiviral activities could be due to the array of secondary metabolites such as tannins, alkaloids, flavonoids, terpenes, anthraquinone, saponins, phenolics, cannabinoid alkaloids, 1,8-cineole, caryophyllene, limonene, α-selinene, β-caryophyllene, germacrene D, cinnamic acid, pyrazol-5-ol, methaqualone, isoquinoline, quinones, reducing sugars, steroids, and volatile oils present in different parts of the plant. The review divulges the ethnobotanical and pharmacological activities of the plant and also justifies the ethnomedical claims. The significant medicinal value of this plant necessitates a scientific adventure into the bioactive metabolites which constitute various extracts.
Highlights
Senna alata is a medicinal herb of Leguminosae family
It is distributed in the tropical and humid regions. e plant is traditionally used in the treatment of typhoid, diabetes, malaria, asthma, ringworms, tinea infections, scabies, blotch, herpes, and eczema. e review is aimed at unveiling the ethnobotanical description and pharmacological activities of S. alata
Antioxidant, antifungal, dermatophytic, anticancer, hepatoprotective, antilipogenic, anticonvulsant, antidiabetic, antihyperlipidemic, antimalarial, anthelmintic, and antiviral activities could be due to the array of secondary metabolites such as tannins, alkaloids, flavonoids, terpenes, anthraquinone, saponins, phenolics, cannabinoid alkaloids, 1,8-cineole, caryophyllene, limonene, α-selinene, β-caryophyllene, germacrene D, cinnamic acid, pyrazol-5-ol, methaqualone, isoquinoline, quinones, reducing sugars, steroids, and volatile oils present in different parts of the plant. e review divulges the ethnobotanical and pharmacological activities of the plant and justifies the ethnomedical claims. e significant medicinal value of this plant necessitates a scientific adventure into the bioactive metabolites which constitute various extracts
Summary
Oluwole Solomon Oladeji ,1,2 Funmilayo Enitan Adelowo, Abimbola Peter Oluyori, and Deborah Temitope Bankole 1. Ese compounds contribute to the apparent medicinal activities displayed by plants and invariably justify the involvement of natural products in the development of novel drugs [5]. Despite these achievements, the use of herbal drugs was not universally accepted in contemporary medicine due to lack of scientific evidence and proper documentation. S. alata, known as Cassia alata, is a widely distributed herb of the Leguminosae family It is commonly known as candle bush, craw-craw plant, acapulo, ringworm bush, or ringworm plant. Is review appraises the ethnobotanical and pharmacological activities of S. alata, justifying diverse traditional applications of the plant In an attempt to resolve these issues, pharmacological research has been tailored towards the discovery of innovative, potent, and safe drugs from natural compounds. is review appraises the ethnobotanical and pharmacological activities of S. alata, justifying diverse traditional applications of the plant
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