Abstract
Platform trials, using adaptive methodologies, have played an important role in the research response to Coronavirus disease 2019 (COVID-19), and offer prospect of being widely used in future pandemic preparedness and response. As these relatively new methodologies raise a number of ethical and governance challenges, in early 2022 the Health Ethics and Governance Unit of the World Health Organization commissioned five rapid reviews, with the aim of learning from, and building on, experiences during the pandemic. These five reviews have been published separately: this short paper provides an introduction to them, sets out the context in which they were produced, and draws together some cross-cutting themes and future directions.
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